Enclomiphene
Testosterone Support
Enclomiphene helps support the body’s natural testosterone production.
Testosterone levels can decline due to age, stress, lifestyle factors, or hormonal imbalance. Lower testosterone levels may contribute to reduced energy, decreased strength, slower recovery, lower libido, and changes in mood or focus.
Enclomiphene is a selective estrogen receptor modulator (SERM) that stimulates your body to produce more testosterone — without replacing testosterone directly the way traditional TRT can. By signaling the pituitary to release LH and FSH, enclomiphene supports the body’s natural testosterone production while helping maintain fertility-related hormone signaling and testicular function.
In a clinical study of men with secondary hypogonadism, 25 mg of enclomiphene daily increased average total testosterone to 604 ± 160 ng/dL after 6 weeks.[1] In another randomized Phase II trial, enclomiphene increased testosterone, LH, and FSH while maintaining sperm counts, unlike topical testosterone therapy.[2]
Potential Benefits
| Increased Testosterone Levels | Stimulates natural testosterone production for improved energy and drive |
| Preserves Fertility | Unlike injectable TRT, maintains sperm production and testicular function |
| Improved Mood & Mental Clarity | Balanced hormones support focus, confidence, and emotional resilience |
| Enhanced Muscle & Body Composition | Supports lean mass development and fat reduction |
| Sustained Natural Production | Works with your body's own hormonal axis, not against it |
How It Works
Enclomiphene works by signaling the hypothalamus and pituitary gland to increase the production of luteinizing hormone (LH) and follicle-stimulating hormone (FSH).
These hormones stimulate the testes to produce more natural testosterone, helping support healthy hormonal balance.
Protocol
Typically administered orally, with dosing determined by a licensed medical provider based on individual needs and health history.
Who It’s For
Individuals seeking support for:
• Low testosterone levels
• Energy and performance
• Strength and recovery
• Hormonal health and vitality
All protocols are reviewed and approved by a licensed medical provider. When prescribed, treatments are compounded and dispensed by licensed U.S. pharmacies operating in compliance with applicable federal and state regulations.
Individual results may vary. Treatments require medical approval following intake review.
References
[1] Wiehle et al. Testosterone restoration using enclomiphene citrate in men with secondary hypogonadism. BJU International.
[2] Wiehle et al. Enclomiphene citrate stimulates testosterone production while preventing oligospermia: a randomized Phase II clinical trial comparing topical testosterone. Fertility and Sterility.
For support: the 604 ± 160 ng/dL figure comes from the 6-week enclomiphene study, and the sperm-count/LH/FSH language is supported by the randomized Phase II trial comparing enclomiphene with topical testosterone.